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Hornady's Critical Defense load for the .22 Mag. was specifically designed for short-barreled handguns. It would appear, however, the company did not intend this stuff to be fired from a handgun with a barrel that is only 1-inch long. Out of the North American Arms Pug, which has a 1-inch barrel, the load did not generate enough velocity to deliver much expansion at all. According to Hornady, from a 2-inch barrel, this load will penetrate about 9 inches and expand more than 1.6 times its original diameter.
| Load | Handgun | MV (fps) | PEN (inches) | EXP (inches) | RW (grains) |
| .22 Mag. Hornady Critical Defense 45-grain FTX | NAA Pug (1-inch barrel) | 733 | 10.75 | .313 | 44 |
